Acknowledgments
Brand new article writers give thanks to Ana Llopart having useful talks and you may comments into the fresh new manuscript and you will Raghu Metpally for bioinformatic help. I plus give thanks to Mohamed Noor, Noor laboratory, Brian Charlesworth, Chuck Langley, and you may about three anonymous reviewers having delivering of good use comments into the manuscript.
Journalist Contributions
Created and customized the latest studies: JMC. Performed this new tests: RR SB. Assessed the info: JMC. Discussed reagents/materials/data products: JMC. Published the newest papers: JMC.
Inclusion
Total, i characterized products of 5,860 ladies meioses and you may genotyped on average forty two,100 educational SNPs for every travel, for all in all, 139 million SNPs. I mapped more than 106,100000 recombination situations (CO and GC shared) which have an average range toward nearest educational SNP away from faster than 2.0 kb (step one.83 kb). Which solution is almost equal to the newest higher-solution mapping from meiotic recombination regarding unicellular S. cerevisiae , 15-flex more than the fresh new linkage map in the A good. thaliana including centered on recombinant inbred contours , and most fifty-bend more in depth than current large-quality whole-genome CO charts for the individuals , C. elegans , C. briggsae , or D. pseudoobscura .
RCO was obtained by comparing crossing over rates from eight crosses (see Materials and Methods for details) and is shown for adjacent 250-kb windows (blue line). The doted red line indicates the P = 0.0005 confidence threshold (equivalent to P ( = 0.05)/number of windows in whole-genome analyses).